Dynamical response properties of neocortical neurons to conductance-driven time-varying inputs
نویسندگان
چکیده
منابع مشابه
The dynamical response properties of neocortical neurons to temporally modulated noisy inputs in vitro.
Cortical neurons are often classified by current-frequency relationship. Such a static description is inadequate to interpret neuronal responses to time-varying stimuli. Theoretical studies suggested that single-cell dynamical response properties are necessary to interpret ensemble responses to fast input transients. Further, it was shown that input-noise linearizes and boosts the response band...
متن کاملThe dynamical response properties of neocortical neurons to temporally modulated noisy inputs in vitro Running title : Neuronal response to fluctuating inputs
Cortical neurons are often classified by current-frequency relationship. Such a static description is inadequate to interpret neuronal responses to time-varying stimuli. Theoretical studies suggested that single-cell dynamical response properties are necessary to interpret ensemble responses to fast input transients. Further, it was shown that input-noise linearizes and boosts the response band...
متن کاملComparison of current-driven and conductance-driven neocortical model neurons with Hodgkin-Huxley voltage-gated channels.
Intrinsic noise and random synaptic inputs generate a fluctuating current across neuron membranes. We determine the statistics of the output spike train of a biophysical model neuron as a function of the mean and variance of the fluctuating current, when the current is white noise, or when it derives from Poisson trains of excitatory and inhibitory postsynaptic conductances. In the first case, ...
متن کاملResponse of spiking neurons to correlated inputs.
The effect of a temporally correlated afferent current on the firing rate of a leaky integrate-and-fire neuron is studied. This current is characterized in terms of rates, autocorrelations, and cross correlations, and correlation time scale tau(c) of excitatory and inhibitory inputs. The output rate nu(out) is calculated in the Fokker-Planck formalism in the limit of both small and large tau(c)...
متن کاملThe discharge variability of neocortical neurons during high-conductance states.
In vivo recordings have shown that the discharge of cortical neurons is often highly variable and can have statistics similar to a Poisson process with a coefficient of variation around unity. To investigate the determinants of this high variability, we analyzed the spontaneous discharge of Hodgkin-Huxley type models of cortical neurons, in which in vivo-like synaptic background activity was mo...
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ژورنال
عنوان ژورنال: European Journal of Neuroscience
سال: 2017
ISSN: 0953-816X
DOI: 10.1111/ejn.13761